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Therefore, in societies where tolerance is the norm, many lactose intolerant people who consume only small amounts of dairy, or have only mild symptoms, may be unaware that they cannot digest lactose. Annual Review of Genomics and Human Genetics. After an overnight fast, blood is drawn and then 50 grams of lactose in aqueous solution are swallowed. From Wikipedia, the free encyclopedia. Main article: Lactase persistence. Therefore, tolerance actually was the norm in most of the societies investigated by early medical researchers.

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There are four general principles in dealing with lactose intolerance: avoidance of dietary lactose, substitution to maintain nutrient intake, regulation of calcium intake, and use of enzyme substitute.

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It functions well only in high-acid environments, such as that found in the human gut due to the addition of gastric juices from the stomach. Lactose is made up of two simple sugars. Lactase enzymes similar to those produced in the small intestines of humans are produced industrially by fungi of the genus Aspergillus. Lactose-sensitive individuals can experiment with both timing and dosage to fit their particular needs.

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